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| Timerman,Artur; Brites,Carlos; Bicudo,Eliana; Grinbaum,Renato S.; Costa Filho,Rubens; Carrilho,Claudia D.M.; Bichels,Andre; Barreto,Tânia. |
| OBJECTIVES: To collect data about non-controlled prescribing use of daptomycin and its impact among Brazilian patients with serious Gram positive bacterial infection, as well as the efficacy and safety outcomes. MATERIALS AND METHODS: This is a multi-center, retrospective, non-interventional registry (August 01, 2009 to June 30, 2011) to collect data on 120 patients (44 patients in the first year and 76 patients in the second year) who had received at least one dose of commercial daptomycin in Brazil for the treatment of serious Gram-positive bacterial infection. RESULTS: Right-sided endocarditis (15.8%), complicated skin and soft tissue infections (cSSTI)wound (15.0%) and bacteremia-catheter-related (14.2%) were the most frequent primary infections; lung... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Daptomycin; Methicillin-resistant; Staphylococcus aureus; Bacteremia; Endocarditis; Skin diseases; Infectious. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000600004 |
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| Ugwu,Clifford C.; Gomez-Sanz,Elena; Agbo,Ifeoma C.; Torres,Carmen; Chah,Kennedy F.. |
| This study was conducted to determine the species distribution, antimicrobial resistance pheno- and genotypes and virulence traits of mannitol-positive methicillin-resistant staphylococci (MRS) isolated from pigs in Nsukka agricultural zone, Nigeria. Twenty mannitol-positive methicillin-resistant coagulase-negative staphylococcal (MRCoNS) strains harboring the mecA gene were detected among the 64 Staphylococcus isolates from 291 pigs. A total of 4 species were identified among the MRCoNS isolates, namely, Staphylococcus sciuri (10 strains), Staphylococcus lentus (6 strains), Staphylococcus cohnii (3 strains) and Staphylococcus haemolyticus (one strain). All MRCoNS isolates were multidrug-resistant. In addition to β-lactams, the strains were resistant to... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Methicillin-resistant; Mannitol-fermenting; Staphylococci; Quinolone resistance; Pigs. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000300885 |
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| Chah,Kennedy F.; Gómez-Sanz,Elena; Nwanta,John A.; Asadu,Brendan; Agbo,Ifeoma C.; Lozano,Carmen; Zarazaga,Myriam; Torres,Carmen. |
| The occurrence, resistance phenotype and molecular mechanisms of resistance of methicillin-resistant staphylococci from groin swabs of 109 clinically healthy dogs in Nsukka, Nigeria were investigated. The groin swab samples were cultured on mannitol salt agar supplemented with 10 µgof cloxacillin. Sixteen methicillin-resistant coagulase negative staphylococci (MRCoNS), all harbouring the mecA gene were isolated from 14 (12.8%) of the 109 dogs studied. The MRCoNS isolated were: S. sciuri subspecies rodentium, S. lentus, S. haemolyticus, and S. simulans with S. sciuri subspecies rodentium (62.5%) being the predominant species. Thirteen (81.3%) of the MRCoNS were resistant to tetracycline while 12 (75%) and 10 (62.5%) were resistant to kanamycin and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Methicillin-resistant; S. sciuri; Resistant genes; Dogs. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000100029 |
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| Cavalcanti,Silvana M.M.; França,Emmanuel R. de; Cabral,Carlos; Vilela,Marinalda A.; Montenegro,Francisco; Menezes,Daniela; Medeiros,Ângela C.R.. |
| Staphylococcus aureus is one of the principal human pathogens that colonize healthy individuals in the community in general, and it is responsible for severe infections in hospitalized patients. Due to an increase in the prevalence of strains of methicillin-resistant S. aureus (MRSA), combating these microorganisms has become increasingly difficult. A descriptive study was carried out on 231 patients in intensive care at the Oswaldo Cruz University Hospital (HUOC) in Recife, Brazil between January and April 2003 to determine the prevalence of S. aureus and MRSA and to evaluate risk factors for colonization by these bacteria when introduced into Intensive Care Units (ICUs). Body secretions were collected from the nostrils, axillary and perineal regions, and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Staphylococcus aureus; Methicillin-resistant; Intensive care unit. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000100010 |
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| Reinert,Cristina; McCulloch,John Anthony; Watanabe,Shinya; Ito,Teruyo; Hiramatsu,Keiichi; Mamizuka,Elsa Masae. |
| Methicillin-resistant Staphylococcus aureus (MRSA) commonly causes infection in hospitalized patients. Since its appearance in the 1960s, the SCCmec has evolved throughout the years into 5 different types (I-V), each bearing a different set of genes. Infection with MRSA SCCmec types I, II or III is almost exclusively restricted to hospitalised patients. However, recently, community acquired MRSA (CA-MRSA) infections have been reported with increasing frequency, usually caused by a type IV SCCmec MRSA in nosocomial settings. We studied the prevalence of SCCmec types in 50 nosocomial strains collected from 1995 to 1999. The SCCmec complex type and presence of Panton-Valentine leukocidin (PVL) were determined by PCR. Strains had been previously typed by PFGE... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Nosocomial infections; Type IV SCCmec; Staphylococcus aureus; Methicillin-resistant; Brazil. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000300010 |
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